mutation class

Gene Expression

synonyms

CLDN18.2 Expression

Claudin-18 Expression

Claudin-18 isoform 2 Expression

A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer

203 sites for NCT03504397

CLDN18 Expression, +1 more biomarker

Adenocarcinoma of the Gastroesophageal Junction, +1 more condition

modified FOLFOX6 regimen, +1 more drug

chemotherapy, +1 more type

A Study to Assess the Efficacy and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

85 sites for NCT03816163

CLDN18 Expression

Pancreatic Adenocarcinoma

gemcitabine, +2 more drugs

chemotherapy, +1 more type

Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT141

3 sites for NCT04683939

CLDN18 Expression

Adenocarcinoma of the Gastroesophageal Junction, +8 more conditions

BNT141, +2 more drugs

chemotherapy, +1 more type

A Study of ZL-1211 in Patients With Advanced Solid Tumor

4 sites for NCT05065710

CLDN18 Expression

Malignant Solid Tumor

ZL-1211

targeted therapy

Study of TJ033721 in Subjects With Advanced or Metastatic Solid Tumors

10 sites for NCT04900818

CLDN18 Expression

Adenocarcinoma of the Gastroesophageal Junction, +4 more conditions

TJ033721

immunotherapy

Study of LM-102 in Subjects in Advanced Tumors

6 sites for NCT04735796

CLDN18 Expression

Malignant Solid Tumor

LM-102

targeted therapy

CT041

CLDN18 Expression

Adenocarcinoma of the Gastroesophageal Junction, +1 more condition

Advanced

CT041

cellular therapy, +1 more type