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Trial Details 79 Other Sites Lincoln, Nebraska

A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011)

This study will compare the efficacy and safety of belzutifan + lenvatinib versus cabozantinib in participants with advanced renal cell carcinoma (RCC) with clear cell component after prior therapy. The primary hypothesis is that belzutifan + lenvatinib is superior to cabozantinib in terms of progression-free survival or overall survival.

phase

Phase 3

status

Recruiting

enrollment

708

score

57

start date

2021-02-25

last updated

2022-01-12

biomarkers

N/A

conditions

condition

Clear Cell Renal Cell Carcinoma

drugs

drug

belzutifan

drug

lenvatinib

primary contact

Toll Free Number

source

clinicaltrials.gov

St. Louis Park, Minnesota

city distance

~445 miles from Lincoln, Nebraska

facility

Cancer Research Center - HealthPartners/Park Nicollet-Oncology Research - Park Nicollet ( Site 0005)

Peoria, Illinois

city distance

~497 miles from Lincoln, Nebraska

facility

Illinois Cancer Care, PC ( Site 0008)

Chicago, Illinois

city distance

~635 miles from Lincoln, Nebraska

facility

Rush University Medical Center ( Site 0040)

Dallas, Texas

city distance

~743 miles from Lincoln, Nebraska

facility

University of Texas, Southwestern Medical Center ( Site 0015)

Grand Rapids, Michigan

city distance

~785 miles from Lincoln, Nebraska

facility

Cancer & Hematology Centers of Western Michigan ( Site 0018)

Fort Wayne, Indiana

city distance

~808 miles from Lincoln, Nebraska

facility

Parkview Cancer Institute ( Site 0088)

Louisville, Kentucky

city distance

~814 miles from Lincoln, Nebraska

facility

Norton Cancer Institute - St. Matthews ( Site 0065)

Atlanta, Georgia

city distance

~1115 miles from Lincoln, Nebraska

facility

Emory University Hospital ( Site 0012)

Athens, Georgia

city distance

~1165 miles from Lincoln, Nebraska

facility

University Cancer & Blood Center, LLC ( Site 0057)

Roanoke, Virginia

city distance

~1246 miles from Lincoln, Nebraska

facility

Blue Ridge Cancer Care - Roanoke ( Site 0043)

Charlotte, North Carolina

city distance

~1264 miles from Lincoln, Nebraska

facility

Levine Cancer Institute ( Site 0004)

Chandler, Arizona

city distance

~1318 miles from Lincoln, Nebraska

facility

Ironwood Cancer & Research Centers ( Site 0077)

79 sites
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Cancer Partners of Nebraska ( Site 0086)
(primary contact)

Study Coordinator