ABemaciclib, ET ± paclItaxel in aGgressive HR+/HER2- MBC trIaL

~61 mi. (León, Spain, +10 more cities)

Complejo Asistencial Universitario De León

ER Positive, +2 more biomarkers

Breast Carcinoma

abemaciclib, +2 more drugs

hormone therapy, +1 more type

Chemotherapy and Imatinib in Young Adults With Acute Lymphoblastic Leukemia Ph (BCR-ABL) POSITIVE

~67 mi. (Tene, Spain, +41 more cities)

Hospital Universitario de Canarias

BCR-ABL1 Fusion, +1 more biomarker

Acute Lymphoblastic Leukemia

cytarabine, +8 more drugs

chemotherapy, +2 more types

A Window-of-opportunity Study of U3-1402, a HER3-targeting Antibody-drug Conjugate in Operable Breast Cancer According to ERBB3 Expression

~67 mi. (Tene, Spain, +7 more cities)

Hospital Universitario de Canarias

ER Positive, +2 more biomarkers

Breast Adenocarcinoma

patritumab deruxtecan

chemotherapy, +1 more type

Selinexor as a Single Agent and in Combination With Imatinib in Patients With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors.

~67 mi. (Tene, Spain, +5 more cities)

Hospital Universitario de Canarias

Gastrointestinal Stromal Tumor

imatinib, +1 more drug

targeted therapy

Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

~84 mi. (Oviedo, Spain, +93 more cities)

Hospital Universitario Central de Asturias ( Site 0654)

Bladder Carcinoma, +1 more condition

cisplatin, +4 more drugs

chemotherapy, +3 more types

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

~84 mi. (Lugo, Spain, +130 more cities)

Hospital Universitario Lucus Augusti ( Site 0852)

Bladder Urothelial Carcinoma

BCG solution, +1 more drug

immunotherapy

Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)

~84 mi. (Oviedo, Spain, +199 more cities)

Hospital Central de Asturias ( Site 0667)

Hepatocellular Carcinoma

pembrolizumab

immunotherapy

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

~84 mi. (Oviedo, Spain, +172 more cities)

Hospital Universitario Central de Asturias

RET Fusion

Non-Small Cell Lung Carcinoma

selpercatinib

targeted therapy

Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) Plus Chemotherapy in Participants With Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-7902-015/E7080-G000-321/LEAP-015)

~84 mi. (Oviedo, Spain, +131 more cities)

Hospital Universitario General de Asturias ( Site 1901)

HER2 Negative

Adenocarcinoma of the Gastroesophageal Junction, +2 more conditions

CAPOX regimen, +3 more drugs

chemotherapy, +2 more types

Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

~84 mi. (Oviedo, Spain, +190 more cities)

Hospital Universitario Central de Asturias

ATM Loss, +27 more biomarkers

Prostate Adenocarcinoma

enzalutamide, +1 more drug

hormone therapy, +1 more type

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014)

~84 mi. (Oviedo, Spain, +45 more cities)

Hospital Universitario General de Asturias ( Site 1601)

Esophageal Squamous Cell Carcinoma

cisplatin, +5 more drugs

chemotherapy, +2 more types

Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013)

~84 mi. (Oviedo, Spain, +122 more cities)

Hospital Universitario Central de Asturias ( Site 1900)

Small Cell Lung Carcinoma

etoposide, +5 more drugs

chemotherapy, +3 more types