Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

~33 mi. (Le Mans, France, +207 more cities)

Clinique Victor Hugo ( Site 0906)

ER Positive, +1 more biomarker

Breast Invasive Ductal Carcinoma

cyclophosphamide, +6 more drugs

chemotherapy, +3 more types

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

~33 mi. (Le Mans, France, +159 more cities)

Clinique Victor Hugo ( Site 0463)

Superficial Bladder Urothelial Carcinoma

cisplatin, +2 more drugs

chemotherapy, +1 more type

A Study of Oral Venetoclax Tablets and Oral Azacitidine Versus Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy

~33 mi. (Le Mans, France, +197 more cities)

Centre Hospitalier du Mans /ID# 215148

BCR-ABL1 Fusion, +47 more biomarkers

Acute Myeloid Leukemia

azacitidine, +1 more drug

chemotherapy

Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

~33 mi. (Le Mans, France, +96 more cities)

Centre Hospitalier Le Mans

Diffuse Large B-Cell Lymphoma, +1 more condition

brentuximab vedotin, +2 more drugs

chemotherapy, +1 more type

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

~33 mi. (Le Mans, France, +142 more cities)

Centre Hospitalier Du Mans - Cancérologie Médicale

del(11)(q10), +27 more biomarkers

Myelofibrosis

imetelstat, +1 more drug

targeted therapy

A Study of Brigatinib Compared to Alectinib in Adults With Non-Small-Cell Lung Cancer

~33 mi. (Le Mans, France, +87 more cities)

Centre Hospitalier Le Mans

ALK Fusion

Non-Small Cell Lung Carcinoma

brigatinib

targeted therapy

A Study to Assess the Efficacy and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

~69 mi. (La Chaussée-Saint-Victor, France, +84 more cities)

Site FR33016

CLDN18 Expression

Pancreatic Adenocarcinoma

gemcitabine, +2 more drugs

chemotherapy, +1 more type

Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL)

~74 mi. (Tours, France, +79 more cities)

CHRU De Tours

Mantle Cell Lymphoma

pirtobrutinib

targeted therapy

A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

~74 mi. (Tours, France, +26 more cities)

CHRU De Tours

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

pirtobrutinib, +2 more drugs

chemotherapy, +2 more types

Study of LOXO-305 Versus Investigator's Choice (IdelaR or BR) in Patients With CLL or SLL

~74 mi. (Tours, France, +71 more cities)

CHRU De Tours

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

pirtobrutinib

targeted therapy

MALIBU Trial - Combination of Ibrutinib and Rituximab in Untreated Marginal Zone Lymphomas

~74 mi. (Tours, France, +34 more cities)

CHU de Tours - Hôpital Bretonneau

MS4A1 Expression

Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue, +2 more conditions

ibrutinib, +1 more drug

immunotherapy, +1 more type

Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)

~82 mi. (Orléans, France, +226 more cities)

Centre Hospitalier Regional du Orleans ( Site 0430)

Prostate Adenocarcinoma

enzalutamide, +1 more drug

hormone therapy, +1 more type