Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

~36 mi. (Des Moines, Iowa, +523 more cities)

Mercy Medical Center - Des Moines, +3 more facilities

Clear Cell Renal Cell Carcinoma

cabozantinib, +2 more drugs

immunotherapy, +1 more type

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

~36 mi. (Des Moines, Iowa, +576 more cities)

Medical Oncology and Hematology Associates-Laurel, +3 more facilities

ERBB2 Amplification, +1 more biomarker

Breast Carcinoma

ado-trastuzumab emtansine, +1 more drug

targeted therapy

Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

~36 mi. (Des Moines, Iowa, +744 more cities)

Iowa Lutheran Hospital, +5 more facilities

Breast Carcinoma

axillary lymph node dissection, +1 more drug

radiation therapy, +1 more type

Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

~36 mi. (Des Moines, Iowa, +269 more cities)

Mercy Medical Center - Des Moines, +1 more facility

ER Positive, +1 more biomarker

Invasive Breast Carcinoma

radiation therapy, +1 more drug

radiation therapy

A Study Comparing Atezolizumab (Anti PD-L1 Antibody) In Combination With Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus Chemotherapy Alone In Patients With Operable Triple-Negative Breast Cancer

~36 mi. (Des Moines, Iowa, +383 more cities)

Des Moines Oncology Research Association

ER Negative, +2 more biomarkers

Breast Carcinoma

atezolizumab, +4 more drugs

chemotherapy, +1 more type

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

~36 mi. (Des Moines, Iowa, +454 more cities)

Blank Children's Hospital, +2 more facilities

Classical Hodgkin Lymphoma

brentuximab vedotin, +7 more drugs

chemotherapy, +3 more types

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

~36 mi. (Des Moines, Iowa, +173 more cities)

Blank Children's Hospital

B-Cell Lymphoblastic Leukemia/Lymphoma

asparaginase Erwinia chrysanthemi, +12 more drugs

chemotherapy, +2 more types

A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy

~36 mi. (Des Moines, Iowa, +233 more cities)

Iowa Methodist Medical Center, +1 more facility

Prostate Adenocarcinoma

degarelix, +4 more drugs

hormone therapy, +1 more type

Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

~36 mi. (Des Moines, Iowa, +244 more cities)

Mercy Medical Center - Des Moines, +5 more facilities

Bladder Urothelial Carcinoma, +4 more conditions

atezolizumab, +4 more drugs

immunotherapy

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

~36 mi. (Des Moines, Iowa, +664 more cities)

Medical Oncology and Hematology Associates-Laurel, +1 more facility

PD-L1 High Expression (TPS >= 1%), +1 more biomarker

Non-Small Cell Lung Carcinoma

carboplatin, +2 more drugs

chemotherapy, +1 more type

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

~36 mi. (Des Moines, Iowa, +825 more cities)

Medical Oncology and Hematology Associates-Laurel, +5 more facilities

AKT1 Mutation, +91 more biomarkers

Breast Carcinoma, +3 more conditions

adavosertib, +26 more drugs

immunotherapy, +1 more type

Testing the Addition of Ixazomib to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma, OPTIMUM Trial

~36 mi. (Des Moines, Iowa, +143 more cities)

Medical Oncology and Hematology Associates-Des Moines, +2 more facilities

Multiple Myeloma

ixazomib, +1 more drug

chemotherapy, +1 more type