Comparative Health Research Outcomes of NOvel Surgery in Prostate Cancer

~7 mi. (Isleworth, United Kingdom, +8 more cities)

West Middlesex Hospital

Prostate Adenocarcinoma

bicalutamide, +3 more drugs

hormone therapy, +1 more type

Study of Pembrolizumab (MK-3475) in Combination With Adjuvant Chemotherapy With or Without Radiotherapy in Participants With Newly Diagnosed Endometrial Cancer After Surgery With Curative Intent (MK-3475-B21 / KEYNOTE-B21 / ENGOT-en11 / GOG-3053)

~8 mi. (Sutton, United Kingdom, +176 more cities)

Royal Marsden Hospital Sutton-Surrey ( Site 2241)

Endometrial Carcinoma, +1 more condition

chemotherapy, +2 more drugs

chemotherapy, +2 more types

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

~8 mi. (Sutton, United Kingdom, +140 more cities)

Royal Marsden NHS Trust ( Site 0693)

Hepatocellular Carcinoma

lenvatinib, +2 more drugs

chemotherapy, +2 more types

A Phase 3 Efficacy, Safety and Tolerability Study of Zolbetuximab (Experimental Drug) Plus mFOLFOX6 Chemotherapy Compared to Placebo Plus mFOLFOX6 as Treatment for Gastric and Gastroesophageal Junction (GEJ) Cancer

~8 mi. (Sutton, United Kingdom, +202 more cities)

Site GB44102

CLDN18 Expression, +1 more biomarker

Adenocarcinoma of the Gastroesophageal Junction, +1 more condition

modified FOLFOX6 regimen, +1 more drug

chemotherapy, +1 more type

Pembrolizumab (MK-3475) Versus Placebo Following Surgery and Radiation in Participants With Locally Advanced Cutaneous Squamous Cell Carcinoma (MK-3475-630/KEYNOTE-630)

~8 mi. (Sutton, United Kingdom, +137 more cities)

Royal Marsden NHS Foundation Trust ( Site 1408)

Skin Squamous Cell Carcinoma

pembrolizumab

immunotherapy

A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (LEAP-010) (MK-7902-010)

~8 mi. (Sutton, United Kingdom, +127 more cities)

Royal Marsden Hospital ( Site 2904)

Hypopharyngeal Squamous Cell Carcinoma, +3 more conditions

lenvatinib, +1 more drug

immunotherapy, +1 more type

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

~8 mi. (Sutton, United Kingdom, +126 more cities)

Royal Marsden Hospital (Sutton) ( Site 0281)

Adenocarcinoma of the Gastroesophageal Junction, +1 more condition

FOLFOX regimen, +3 more drugs

chemotherapy, +2 more types

A Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)

~8 mi. (Sutton, United Kingdom, +35 more cities)

Royal Marsden NHS Trust ( Site 1063)

Colorectal Adenocarcinoma

favezelimab, +1 more drug

immunotherapy

A Study of LOXO-292 in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer

~8 mi. (Sutton, United Kingdom, +78 more cities)

Royal Marsden Hospital

RET Fusion, +1 more biomarker

Adrenal Gland Pheochromocytoma, +5 more conditions

selpercatinib

targeted therapy

Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

~8 mi. (Sutton, United Kingdom, +69 more cities)

The Royal Marsden Hospital (Surrey)

Cervical Adenocarcinoma, +2 more conditions

tisotumab vedotin

chemotherapy, +1 more type

177Lu-PSMA-617 vs. Androgen Receptor-directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer

~8 mi. (Sutton, United Kingdom, +41 more cities)

Novartis Investigative Site

Prostate Adenocarcinoma

lutetium Lu 177 vipivotide tetraxetan

radiation therapy, +1 more type

A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid Cancer

~8 mi. (Sutton, United Kingdom, +143 more cities)

Royal Marsden Hospital

RET Mutation

Thyroid Gland Medullary Carcinoma

selpercatinib

targeted therapy