Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

~40 mi. (Belpre, Ohio, +523 more cities)

Strecker Cancer Center-Belpre

Clear Cell Renal Cell Carcinoma

cabozantinib, +2 more drugs

immunotherapy, +1 more type

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

~40 mi. (Belpre, Ohio, +576 more cities)

Strecker Cancer Center-Belpre

ERBB2 Amplification, +1 more biomarker

Breast Carcinoma

ado-trastuzumab emtansine, +1 more drug

targeted therapy

Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

~40 mi. (Belpre, Ohio, +744 more cities)

Strecker Cancer Center-Belpre

Breast Carcinoma

axillary lymph node dissection, +1 more drug

radiation therapy, +1 more type

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

~40 mi. (Belpre, Ohio, +664 more cities)

Strecker Cancer Center-Belpre

PD-L1 High Expression (TPS >= 1%), +1 more biomarker

Non-Small Cell Lung Carcinoma

carboplatin, +2 more drugs

chemotherapy, +1 more type

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

~40 mi. (Belpre, Ohio, +825 more cities)

Strecker Cancer Center-Belpre

AKT1 Mutation, +91 more biomarkers

Breast Carcinoma, +3 more conditions

adavosertib, +26 more drugs

immunotherapy, +1 more type

Testing the Addition of Ixazomib to Lenalidomide in Patients With Evidence of Residual Multiple Myeloma, OPTIMUM Trial

~40 mi. (Belpre, Ohio, +143 more cities)

Strecker Cancer Center-Belpre

Multiple Myeloma

ixazomib, +1 more drug

chemotherapy, +1 more type

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

~40 mi. (Belpre, Ohio, +327 more cities)

Strecker Cancer Center-Belpre

Multiple Myeloma

bortezomib, +3 more drugs

chemotherapy, +3 more types

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

~40 mi. (Belpre, Ohio, +656 more cities)

Strecker Cancer Center-Belpre

Deficient DNA Mismatch Repair (dMMR), +8 more biomarkers

Colon Adenocarcinoma, +1 more condition

atezolizumab, +3 more drugs

chemotherapy, +1 more type

S0820, Adenoma and Second Primary Prevention Trial

~40 mi. (Belpre, Ohio, +616 more cities)

Strecker Cancer Center-Belpre

Colon Carcinoma, +1 more condition

eflornithine, +2 more drugs

chemotherapy, +1 more type

Nivolumab and Ipilimumab in Treating Patients With Rare Tumors

~40 mi. (Belpre, Ohio, +606 more cities)

Strecker Cancer Center-Belpre

CD274 Amplification

Angiosarcoma, +26 more conditions

ipilimumab, +1 more drug

immunotherapy

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

~40 mi. (Belpre, Ohio, +497 more cities)

Strecker Cancer Center-Belpre

HER2 Positive

Breast Adenocarcinoma

atezolizumab, +4 more drugs

chemotherapy, +2 more types

S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration

~40 mi. (Belpre, Ohio, +405 more cities)

Strecker Cancer Center-Belpre

Multiple Myeloma

daratumumab/hyaluronidase, +1 more drug

chemotherapy, +2 more types