Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

~12 mi. (Le Mans, France, +207 more cities)

Clinique Victor Hugo ( Site 0906)

ER Positive, +1 more biomarker

Breast Invasive Ductal Carcinoma

cyclophosphamide, +6 more drugs

chemotherapy, +3 more types

Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)

~12 mi. (Le Mans, France, +159 more cities)

Clinique Victor Hugo ( Site 0463)

Superficial Bladder Urothelial Carcinoma

cisplatin, +2 more drugs

chemotherapy, +1 more type

A Study of Oral Venetoclax Tablets and Oral Azacitidine Versus Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy

~12 mi. (Le Mans, France, +197 more cities)

Centre Hospitalier du Mans /ID# 215148

BCR-ABL1 Fusion, +47 more biomarkers

Acute Myeloid Leukemia

azacitidine, +1 more drug

chemotherapy

Brentuximab Vedotin Plus Lenalidomide and Rituximab for the Treatment of Relapsed/Refractory DLBCL

~12 mi. (Le Mans, France, +96 more cities)

Centre Hospitalier Le Mans

Diffuse Large B-Cell Lymphoma, +1 more condition

brentuximab vedotin, +2 more drugs

chemotherapy, +1 more type

A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment

~12 mi. (Le Mans, France, +142 more cities)

Centre Hospitalier Du Mans - Cancérologie Médicale

del(11)(q10), +27 more biomarkers

Myelofibrosis

imetelstat, +1 more drug

targeted therapy

A Study of Brigatinib Compared to Alectinib in Adults With Non-Small-Cell Lung Cancer

~12 mi. (Le Mans, France, +87 more cities)

Centre Hospitalier Le Mans

ALK Fusion

Non-Small Cell Lung Carcinoma

brigatinib

targeted therapy

Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL)

~54 mi. (Tours, France, +79 more cities)

CHRU De Tours

Mantle Cell Lymphoma

pirtobrutinib

targeted therapy

A Trial of Pirtobrutinib (LOXO-305) Plus Venetoclax and Rituximab (PVR) Versus Venetoclax and Rituximab (VR) in Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

~54 mi. (Tours, France, +26 more cities)

CHRU De Tours

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

pirtobrutinib, +2 more drugs

chemotherapy, +2 more types

Study of LOXO-305 Versus Investigator's Choice (IdelaR or BR) in Patients With CLL or SLL

~54 mi. (Tours, France, +71 more cities)

CHRU De Tours

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

pirtobrutinib

targeted therapy

MALIBU Trial - Combination of Ibrutinib and Rituximab in Untreated Marginal Zone Lymphomas

~54 mi. (Tours, France, +34 more cities)

CHU de Tours - Hôpital Bretonneau

MS4A1 Expression

Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue, +2 more conditions

ibrutinib, +1 more drug

immunotherapy, +1 more type

A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012)

~61 mi. (Angers, France, +144 more cities)

CHU Angers ( Site 1200)

Clear Cell Renal Cell Carcinoma

belzutifan, +3 more drugs

immunotherapy, +1 more type

A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011)

~61 mi. (Angers, France, +93 more cities)

Institut de Cancerologie de l Ouest Site Paul Papin ( Site 1200)

Clear Cell Renal Cell Carcinoma

belzutifan, +1 more drug

targeted therapy