Immunotherapy With Nivolumab and Ipilimumab Followed by Nivolumab or Nivolumab With Cabozantinib for Patients With Advanced Kidney Cancer, The PDIGREE Study

~16 mi. (Allentown, Pennsylvania, +523 more cities)

Lehigh Valley Hospital-Cedar Crest

Clear Cell Renal Cell Carcinoma

cabozantinib, +2 more drugs

immunotherapy, +1 more type

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

~16 mi. (Allentown, Pennsylvania, +576 more cities)

Lehigh Valley Hospital-Cedar Crest

ERBB2 Amplification, +1 more biomarker

Breast Carcinoma

ado-trastuzumab emtansine, +1 more drug

targeted therapy

Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

~16 mi. (Allentown, Pennsylvania, +744 more cities)

Lehigh Valley Hospital-Cedar Crest

Breast Carcinoma

axillary lymph node dissection, +1 more drug

radiation therapy, +1 more type

Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma

~16 mi. (Allentown, Pennsylvania, +454 more cities)

Lehigh Valley Hospital-Cedar Crest

Classical Hodgkin Lymphoma

brentuximab vedotin, +7 more drugs

chemotherapy, +3 more types

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

~16 mi. (Allentown, Pennsylvania, +173 more cities)

Lehigh Valley Hospital-Cedar Crest

B-Cell Lymphoblastic Leukemia/Lymphoma

asparaginase Erwinia chrysanthemi, +12 more drugs

chemotherapy, +2 more types

A Clinical Study Evaluating The Benefit of Adding Rucaparib to Enzalutamide for Men With Metastatic Prostate Cancer That Has Become Resistant To Testosterone-Deprivation Therapy

~16 mi. (Allentown, Pennsylvania, +233 more cities)

Lehigh Valley Hospital-Cedar Crest

Prostate Adenocarcinoma

degarelix, +4 more drugs

hormone therapy, +1 more type

Trying to Find the Correct Length of Treatment With Immune Checkpoint Therapy

~16 mi. (Allentown, Pennsylvania, +244 more cities)

Lehigh Valley Hospital-Cedar Crest

Bladder Urothelial Carcinoma, +4 more conditions

atezolizumab, +4 more drugs

immunotherapy

A Study of Nivolumab or Placebo in Combination With Docetaxel in Men With Advanced Castration-resistant Prostate Cancer

~16 mi. (Allentown, Pennsylvania, +271 more cities)

Lehigh Valley Health Network

Prostate Adenocarcinoma

docetaxel, +2 more drugs

chemotherapy, +2 more types

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

~16 mi. (Allentown, Pennsylvania, +664 more cities)

Lehigh Valley Hospital-Cedar Crest

PD-L1 High Expression (TPS >= 1%), +1 more biomarker

Non-Small Cell Lung Carcinoma

carboplatin, +2 more drugs

chemotherapy, +1 more type

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

~16 mi. (Allentown, Pennsylvania, +825 more cities)

Lehigh Valley Hospital-Cedar Crest

AKT1 Mutation, +91 more biomarkers

Breast Carcinoma, +3 more conditions

adavosertib, +26 more drugs

immunotherapy, +1 more type

Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

~16 mi. (Allentown, Pennsylvania, +240 more cities)

Lehigh Valley Hospital-Cedar Crest

Endometrial Adenocarcinoma, +5 more conditions

carboplatin, +2 more drugs

chemotherapy, +1 more type

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

~16 mi. (Allentown, Pennsylvania, +327 more cities)

Lehigh Valley Hospital-Cedar Crest

Multiple Myeloma

bortezomib, +3 more drugs

chemotherapy, +3 more types