Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)

~15 mi. (Pozzuoli, Italy, +226 more cities)

Presidio Ospedaliero S. Maria Delle Grazie-U.O.C. ONCOLOGIA ( Site 0802)

Prostate Adenocarcinoma

enzalutamide, +1 more drug

hormone therapy, +1 more type

Perioperative Enfortumab Vedotin (EV) Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle Invasive Bladder Cancer (MIBC) (MK-3475-B15/ KEYNOTE-B15 / EV-304)

~15 mi. (Pozzuoli, Italy, +93 more cities)

Presidio Ospedaliero Santa Maria delle Grazie ( Site 0599)

Bladder Carcinoma, +1 more condition

cisplatin, +4 more drugs

chemotherapy, +3 more types

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

~20 mi. (Naples, Italy, +192 more cities)

University of Naples Federico II

ER Positive, +1 more biomarker

Breast Carcinoma

abemaciclib, +1 more drug

hormone therapy, +1 more type

Pembrolizumab/Vibostolimab Coformulation (MK-7684A) or Pembrolizumab/Vibostolimab Coformulation Plus Docetaxel Versus Docetaxel for Metastatic Non Small Cell Lung Cancer (NSCLC) With Progressive Disease After Platinum Doublet Chemotherapy and Immunotherapy (MK-7684A-002)

~20 mi. (Naples, Italy, +76 more cities)

Azienda Ospedaliera Dei Colli-U.O.C Pneumologia Oncologica DH PNL ONC ( Site 1308)

Non-Small Cell Lung Carcinoma

docetaxel, +1 more drug

chemotherapy, +1 more type

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL) or Pancreatic Neuroendocrine Tumor (pNET) (MK-6482-015)

~20 mi. (Naples, Italy, +29 more cities)

University of Naples Federico II-Dipartimento di Medicina Clinica e Chirurgia ( Site 0704)

Pancreatic Neuroendocrine Tumor, +1 more condition

belzutifan

targeted therapy

A Study of Rituximab-Gemcitabine-Dexamethasone-Platinum (R-GDP) With or Without Selinexor in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

~20 mi. (Naples, Italy, +44 more cities)

National Cancer Institute

BCL2 Fusion, +2 more biomarkers

Diffuse Large B-Cell Lymphoma, +3 more conditions

cisplatin, +5 more drugs

chemotherapy, +3 more types

A Study Comparing Atezolizumab (Anti PD-L1 Antibody) In Combination With Adjuvant Anthracycline/Taxane-Based Chemotherapy Versus Chemotherapy Alone In Patients With Operable Triple-Negative Breast Cancer

~33 mi. (Napoli, Italy, +383 more cities)

Istituto Nazionale Tumori Irccs Fondazione g. PASCALE;U.O.C. Oncologia Medica Senologica

ER Negative, +2 more biomarkers

Breast Carcinoma

atezolizumab, +4 more drugs

chemotherapy, +1 more type

Safety and Efficacy of Lenvatinib (E7080/MK-7902) With Pembrolizumab (MK-3475) in Combination With Transarterial Chemoembolization (TACE) in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma (MK-7902-012/E7080-G000-318/LEAP-012)

~33 mi. (Napoli, Italy, +140 more cities)

Ospedale del Mare ( Site 0327)

Hepatocellular Carcinoma

lenvatinib, +2 more drugs

chemotherapy, +2 more types

Investigation of Radium-223 Dichloride (Xofigo), a Treatment That Gives Off Radiation That Helps Kill Cancer Cells, Compared to a Treatment That Inactivates Hormones (New Antihormonal Therapy, NAH) in Patients With Prostate Cancer That Has Spread to the Bone Getting Worse on or After Earlier NAH

~33 mi. (Napoli, Italy, +122 more cities)

A.O.R.N. Antonio Cardarelli

Prostate Adenocarcinoma

radium Ra 223 dichloride

radiation therapy

A Study Evaluating the Efficacy and Safety of Giredestrant Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Participants With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer (persevERA Breast Cancer)

~33 mi. (Napoli, Italy, +262 more cities)

Istituto Nazionale per lo Studio e la Cura dei Tumori Fondazione G. Pascale

ER Positive, +1 more biomarker

Breast Adenocarcinoma

giredestrant, +2 more drugs

hormone therapy, +1 more type

Study of Talazoparib With Enzalutamide in Men With DDR Gene Mutated mCSPC

~33 mi. (Napoli, Italy, +190 more cities)

Istituto Nazionale Tumori IRCCS Fondazione G. Pascale - Napoli

ATM Loss, +27 more biomarkers

Prostate Adenocarcinoma

enzalutamide, +1 more drug

hormone therapy, +1 more type

A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy

~33 mi. (Napoli, Italy, +260 more cities)

Università degli Studi Federico II; Clinica di Oncologia Medica, +1 more facility

ERBB2 Amplification, +1 more biomarker

Invasive Breast Carcinoma

ado-trastuzumab emtansine, +1 more drug

immunotherapy, +1 more type