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Study of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-3475-641/KEYNOTE-641)
city
~37 mi. (Cambridge, United Kingdom, +226 more cities)
facility
Cambridge University Hospitals NHS Trust ( Site 0540)
drug
enzalutamide, +1 more drug
drug type
hormone therapy, +1 more type
Safety and Efficacy of Pembrolizumab (MK-3475) Versus Placebo as Adjuvant Therapy in Participants With Hepatocellular Carcinoma (HCC) and Complete Radiological Response After Surgical Resection or Local Ablation (MK-3475-937 / KEYNOTE-937)
city
~37 mi. (Cambridge, United Kingdom, +199 more cities)
facility
Cambridge University Hospitals NHS Trust ( Site 0755)
Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)
city
~37 mi. (Cambridge, United Kingdom, +126 more cities)
facility
Cambridge University Hospitals NHS Trust ( Site 0477)
drug
FOLFOX regimen, +3 more drugs
drug type
chemotherapy, +2 more types
Platinum and Polyadenosine 5'Diphosphoribose Polymerisation (PARP) Inhibitor for Neoadjuvant Treatment of Triple Negative Breast Cancer (TNBC) and/or Germline BRCA (gBRCA) Positive Breast Cancer
city
~37 mi. (Cambridge, United Kingdom)
facility
Cambridge University Hospitals NHS Foundation Trust & the University of Cambridge
biomarker
BRCA1 Loss, +6 more biomarkers
drug
carboplatin, +2 more drugs
drug type
chemotherapy, +1 more type
A Pre-operative Window Study of Letrozole Plus PR Agonist (Megestrol Acetate) Versus Letrozole Alone in Post-menopausal Patients With ER-positive Breast Cancer
city
~37 mi. (Cambridge, United Kingdom)
facility
Cambridge University Hospitals NHS Foundation Trust
biomarker
ER Positive, +1 more biomarker
drug
letrozole, +1 more drug
Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)
city
~41 mi. (Norwich, United Kingdom, +159 more cities)
facility
Norfolk & Norwich University Hospital NHS Foundation Trust ( Site 0725)
drug
cisplatin, +2 more drugs
drug type
chemotherapy, +1 more type