Trial Details 579 Total Sites

Comparison of Axillary Lymph Node Dissection With Axillary Radiation for Patients With Node-Positive Breast Cancer Treated With Chemotherapy

This randomized phase III trial studies lymph node dissection and radiation therapy to see how well it works compared to radiation therapy alone in treating patients with breast cancer previously treated with chemotherapy and surgery. Lymph node dissection may remove cancer cells that have spread to nearby lymph nodes in patients with breast cancer. Radiation therapy uses high-energy x rays or protons to kill tumor cells. It is not yet known if radiation therapy works better alone or with lymph node dissection in treating patients with breast cancer previously treated with chemotherapy and surgery.

phase

Phase 3

status

Recruiting

enrollment

1660

score

61

start date

2014-02-28

last updated

2022-01-11

biomarkers

N/A

New York City, New York
facility
Mount Sinai West
facility
NYP/Weill Cornell Medical Center
+4 more facilities
6 facilities
Recruiting
Los Angeles, California
facility
Cedars Sinai Medical Center
facility
USC / Norris Comprehensive Cancer Center
+1 more facilities
3 facilities
Recruiting
Chicago, Illinois
facility
Advocate Illinois Masonic Medical Center
facility
Mount Sinai Hospital Medical Center
+4 more facilities
6 facilities
Recruiting
Brooklyn, New York
facility
New York-Presbyterian/Brooklyn Methodist Hospital
1 facility
Recruiting
Houston, Texas
facility
M D Anderson Cancer Center
facility
MD Anderson West Houston
2 facilities
Recruiting
Philadelphia, Pennsylvania
facility
Thomas Jefferson University Hospital
1 facility
Recruiting
Phoenix, Arizona
facility
Arizona Breast Cancer Specialists-Phoenix
facility
Cancer Center at Saint Joseph's
2 facilities
Recruiting
San Diego, California
facility
Sharp Memorial Hospital
1 facility
Recruiting
San Jose, California
facility
Kaiser Permanente-Santa Teresa-San Jose
1 facility
Recruiting
Jacksonville, Florida
facility
Mayo Clinic in Florida
1 facility
Recruiting
San Francisco, California
facility
California Pacific Medical Center-Pacific Campus
facility
Kaiser Permanente-San Francisco
2 facilities
Recruiting
Columbus, Ohio
facility
Columbus Oncology and Hematology Associates Inc
facility
Riverside Methodist Hospital
+6 more facilities
8 facilities
Recruiting